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Message definition (Trigeminal Nervous System Segmentation)
Headache is oftes associated with a ‘sensitization’ of the nociceptive trigeminal system with the involvement of anti-nocicective mesenchephalic structures such as periaqueductal substance, locus coeruleus, and the nuclei of the raphe, which have a modulator effect on trigeminal sensitive nuclei

Headache is oftes associated with a ‘sensitization’ of the nociceptive trigeminal system with the involvement of anti-nocicective mesenchephalic structures such as periaqueductal substance, locus coeruleus, and the nuclei of the raphe, which have a modulator effect on trigeminal sensitive nuclei

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