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----{{ArtBy|autore=Gianni Frisardi}}
----{{ArtBy|autore=Gianni Frisardi}}
==Ab ovo<ref>Latin for 'since the very beginning'</ref>==


Before diving into the analysis of Masticationpedia, it is necessary to introduce some preliminary considerations. These concern, in particular, two fundamental dimensions - social, scientific, and clinical - that are characteristic of both the current era and the one immediately preceding it.
<Div class="colour-button">[[Special:UserLogin&returnto=Introduction+Page|Read the full chapter]]  
 
=== The phases of paradigm change according to Thomas Kuhn===
[[File:The phases of paradigm change according to Thomas Kuhn.jpg|right|thumb|The phases of paradigm change according to Thomas Kuhn]]In the course of the last century, there has been an exponential increase in technological and methodological "Innovations",<ref>{{cita libro
| autore = Heft MW
| autore2 = Fox CH
| autore3 = Duncan RP
| titolo = Assessing the Translation of Research and Innovation into Dental Practice
| url = https://www.ncbi.nlm.nih.gov/pubmed/31590599
| volume =
| opera = JDR Clin Trans Res
| anno = 2019
| editore =
| città =
| ISBN =
| LCCN =
| DOI = 10.1177/2380084419879391
| OCLC =
}} Oct 7:2380084419879391</ref> especially in the field of dentistry. These advancements have significantly influenced decision-making strategies, opinions, schools of thought, and axioms, aiming explicitly at improving the quality of life, as highlighted in the "Science of Exposure in the 21st Century".<ref>{{cita libro
| autore =
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| titolo = Exposure Science in the 21st Century. A Vision and a Strategy
| url = https://www.ncbi.nlm.nih.gov/books/NBK206806/pdf/Bookshelf_NBK206806.pdf
| volume =
| opera =
| anno =
| editore = Committee on Human and Environmental Exposure Science in the 21st Century; Board on Environmental Studies and Toxicology; Division on Earth and Life Studies; National Research Council.
| città =
| ISBN = 0-309-26468-5
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}}</ref> However, this exponential growth implicitly hides conceptual ambiguities - or, in practical terms, "side effects" - which, although sometimes underestimated, have the power to challenge some scientific certainties, making them less rigid and more subject to probability.<ref>{{cita libro
| autore = Liu L
| autore2 = Li Y
| titolo = The unexpected side effects and safety of therapeutic monoclonal antibodies
| url = https://www.ncbi.nlm.nih.gov/pubmed/24524104
| volume =
| opera = Drugs Today
| anno = 2014
| editore =
| città = Barcellona
| ISBN =
| LCCN =
| DOI = 10.1358/dot.2014.50.1.2076506
| OCLC =
}} Jan;50(1):33-50</ref> The sensitive aspects of the current social, scientific, and clinical reality, which may seem contrasting, will be revealed to be complementary by the end of this reading; this is the "Progress of science" according to Kuhn's interpretation and "Epistemology".
 
In analyzing the progress of science, Thomas Kuhn, in his most famous work, argues that science develops through distinct cycles, reflecting its operational dynamics.<ref>Thomas Samuel Kuhn (Cincinnati, 18 luglio 1922 – Cambridge, 17 giugno 1996) was an American philosopher of science.<br>See Treccani, ''[http://www.treccani.it/enciclopedia/thomas-samuel-kuhn/ Kuhn, Thomas Samuel]''. Or Wikipedia, ''[[:wpen:Thomas Kuhn|Thomas Kuhn]]''.
</ref><ref>{{cita libro
| autore = Kuhn Thomas S
| titolo = The Structure of Scientific Revolutions
| url = https://en.wikipedia.org/wiki/The_Structure_of_Scientific_Revolutions
| volume =
| opera =
| anno = 2012
| editore = Univ. of Chicago Press
| città = Chicago
| ISBN = 9780226458113
| LCCN = no99080311
| DOI =
| OCLC =
}}</ref> Kuhn advances the idea that science is structured around paradigms and establishes a clear demarcation between science and pseudoscience, based on the presence of a shared paradigm. For him, the evolution of scientific progress is seen as a continuous curve, yet interrupted by discontinuities represented by paradigm shifts.
 
Taking on the role of a skilled problem solver, the scientist is engaged in resolving these anomalies. These moments of discontinuity, or scientific revolutions, occur when the existing paradigm can no longer adequately interpret new anomalies, thereby pushing the scientific community towards the exploration and eventual adoption of new paradigms that better align with emerging observations.
 
===='''Kuhn's phases in Dentistry'''====
Thomas Kuhn identifies in the evolution of a scientific paradigm five distinct phases, a process that holds crucial importance for Masticationpedia. To stay in line with the project's objectives, we will focus on the description of the three most significant phases, as outlined in the book's index.
 
'''Thomas Kuhn''' in his most famous work states that ''science cyclically passes through some phases indicative of its operation''. According to Kuhn, ''science is paradigmatic'', and the demarcation between science and pseudoscience can be traced back to the existence of a '''paradigm'''. The evolution of scientific progress is assimilated to ''a continuous curve which undergoes discontinuity in paradigm changes''. 
 
===Kuhn's phases in Dentistry===
 
Kuhn, on the other hand, divides the evolution of a paradigm into five phases; this is a fundamental process for Masticationpedia, but to stay tuned with the project we will limit ourselves to describing the three most significant phases shared in the project and indicated in the index of the book:
 
It's almost taken for granted that Kuhn's scientific philosophy gives priority to discipline, since an anomaly within the genetic paradigm will be more easily recognized by a geneticist rather than a neurophysiologist. This concept, however, seems to contradict the epistemological evolution of Science, thereby making a detailed analysis of this apparent discrepancy appropriate.
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==Epistemology==
<center>
{|
|-
| align="right" width="250" |<small>''The black swan symbolizes one of the historical problems of epistemology: if all the swans we have seen so far are white, can we decide that all the swans are white?<br>Really?''</small>
| align="center" |[[File:Black_Swan_(Cygnus_atratus)_RWD.jpg|175px|center]]
|-
|&nbsp;
|-
| align="center" |[[File:Duck-Rabbit illusion.jpg|203px|center]]
| width="250" |<small>''Kuhn used optical illusion to demonstrate how a paradigm shift can cause a person to see the same information in a completely different way: which animal is the one here aside?<br>Sure?''</small>
|}
</center>
 
 
'''Epistemology''' (from the Greek ἐπιστήμη, epistēmē, meaning "certain knowledge" or "science", and λόγος, logos, "discourse") represents that branch of philosophy dedicated to the study of the necessary conditions for acquiring scientific knowledge and the methods through which such knowledge can be achieved.<ref>The term is believed to have been coined by the Scottish philosopher [[:wpen:James Frederick Ferrier|James Frederick Ferrier]], in his '' Institutes of Metaphysic '' (p.46), of 1854; see Internet Encyclopedia of Philosophy, ''[https://www.iep.utm.edu/ferrier/ James Frederick Ferrier (1808—1864)]''.</ref> This term specifically refers to that section of gnoseology that investigates the foundations, the validity, and the limits of scientific knowledge. In English-speaking countries, the concept of epistemology is commonly employed almost as a synonym for gnoseology or theory of knowledge, that is, the discipline that examines the study of knowledge in general.
 
It is important to emphasize that the central problem of epistemology, today as in the times of Hume, is the issue of verifiability.<ref>[[:wpen:David Hume|David Hume]] (Edimburgo, 7 maggio 1711[1] – Edimburgo, 25 agosto 1776) was a Scottish philosopher. He is considered the third and perhaps the most radical of the British Empiricists, after the Englishman John Locke and the Anglo-Irish George Berkeley.</ref><ref>{{cita libro
| autore = Srivastava S
| titolo = Verifiability is a core principle of science
| url = https://www.cambridge.org/core/journals/behavioral-and-brain-sciences/article/verifiability-is-a-core-principle-of-science/D46462A598492AFDB7AFB4975A313446#
| volume =
| opera = Behav Brain Sci
| anno = 2018
| editore = Cambridge University Press
| città = Cambridge
| ISBN =
| LCCN =
| DOI = 10.1017/S0140525X18000869
| OCLC =
}} Jan;41:e150. </ref>
 
The Hempel's paradox asserts that the observation of every white swan provides support to the statement that all ravens are black;<ref>Here we obviously refer to the well-known paradox called "of the crows", or "of the black crows", formulated by the philosopher and mathematician [[:wpen:Carl Gustav Hempel|Carl Gustav Hempel]], better explained in Wikipedia's article ''[https://en.wikipedia.org/w/index.php?title=Raven_paradox&oldid=942633026 Raven paradox]'':<br>See {{cita libro
|autore = Good IJ
|titolo=The Paradox of Confirmation
|opera=Br J Philos Sci
|volume=11
|numero=42
|url=https://www.jstor.org/stable/685588
|anno = 1960|pag=145-149}}</ref> in other words, every example that does not contradict the theory confirms a part of it. According to this paradox:
 
<math>A\Rightarrow B = \lnot A \lor B</math>
 
According to the criterion of falsifiability, no theory can be considered definitively true, as although there is only a finite number of experiments that can confirm it, theoretically there is an infinite number of experiments that could refute it.<ref>{{cita libro
| autore = Evans M
| titolo = Measuring statistical evidence using relative belief
| url = https://www.ncbi.nlm.nih.gov/pubmed/26925207
| volume =
| opera = Comput Struct Biotechnol J
| anno = 2016
| editore =
| città =
| ISBN =
| LCCN =
| DOI = 10.1016/j.csbj.2015.12.001
| OCLC =
}} Jan 7;14:91-6. </ref>
 
{{qnq|But it’s not all so obvious...}}
 
...because the very concept of epistemology meets continuous implementations, like in medicine:
 
==Anomaly ''vs.'' Interdisciplinarity==
 
A superficial view might suggest that the epistemic evolution of science is marked by an apparent opposition between the aspects of disciplinarity, highlighted by the "Physics Paradigm of Science" (which sheds light on anomalies), and those of interdisciplinarity, represented by the "Engineering Paradigm of Science" (and the related concept of metacognitive scaffold). However, as will be explored in this chapter, these two perspectives are not actually in conflict; on the contrary, they prove to be complementary, as both contribute to the generation of a "Paradigmatic Innovation" without any form of conflict.
 
It could then be argued that "Innovations" themselves represent "Progresses of Science," as illustrated in the article "Scientific Bases of Dentistry" by Yegane Guven. This work explores the impact of biological and digital revolutions on education and daily clinical practice in dentistry, covering topics such as personalized regenerative dentistry, nanotechnologies, virtual reality simulations, genomic information, and stem cell research.<ref>{{cita libro
| autore = Guven Y
| titolo = Scientific basis of dentistry
| url = https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5624148/
| volume =
| opera = J Istanb Univ Fac Den
| anno = 2017
| editore =
| città =
| ISBN =
| LCCN =
| DOI = 10.17096/jiufd.04646
| OCLC =
}} 51(3): 64–71. Published online 2017 Oct 2. PMCID: PMC5624148 - PMID: 29114433 </ref> Although the innovations mentioned are technological and methodological in nature, it is crucial to recognize that true scientific progress does not occur exclusively through "Incremental Innovations" or "Radical Innovations," but is fundamentally achieved through "Paradigmatic Innovations."
 
In the strictest sense of the term, "Paradigmatic Innovations" are a change in thinking and awareness that spreads throughout all of humanity, affecting different social layers, from the Copernican revolution to the recent trend of approaching biological phenomena with a stochastic method.<ref>{{cita libro
| autore = Zhao XF
| autore2 = Gojo I
| autore3 = York T
| autore4 = Ning Y
| autore5 = Baer MR
| titolo = Diagnosis of biphenotypic acute leukemia: a paradigmatic approach
| url = https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2776262
| volume =
| opera = Int J Clin Exp Pathol
| anno = 2010
| editore =
| città =
| ISBN =
| LCCN =
| DOI =
| OCLC =
}} Prepublished online 2009 Oct 10. PMCID: PMC2776262 - PMID: 19918331. 3(1): 75–86.</ref>
 
This epistemological context, which includes initiatives such as the Research Diagnostic Criteria for Temporomandibular Disorders (RDC/TMD), Evidence-Based Medicine, and others, is further explored in the Masticationpedia project. The latter aims to highlight the dynamics and dialectics of progress in the science of masticatory rehabilitations, emphasizing the anomalies that stimulate a change in thought and, consequently, a "Paradigmatic Innovation."
 
Before proceeding, it might be appropriate to observe a very concrete and significant case.
 
==Malocclusion==
 
"Malocclusion" derives from the Latin "malum," meaning "bad" or "wrong," and literally refers to an improper closure of the teeth.<ref>The creation of the term is generally attributed to [[:wpen:Edward Angle|Edward Angle]], considered the father of modern orthodontics, who coined it as a specification of ''occlusion'' to signal the incorrect opposition in closing of the lower teeth and upper, especially the first molar; see {{cita libro
| autore = Gruenbaum T
| titolo = Famous Figures in Dentistry
| url =
| volume =
| opera = Mouth – JASDA
| anno = 2010
| editore =
| città =
| ISBN =
| LCCN =
| DOI =
| OCLC =
}}, 30(1):18. </ref> The notion of "closure" may seem intuitive; however, the adjective "bad" requires careful consideration, as its application in the medical context is less obvious than it may appear.
 
To approach an understanding of the term, this introduction poses a seemingly simple yet profoundly complex question, which in turn raises a series of related inquiries in the field of masticatory rehabilitation and, more specifically, in orthodontic disciplines: what exactly is meant by "Malocclusion"? It's interesting to note that, in 2019, a search for the term "Malocclusion" on PubMed yielded a whopping 33,309 articles,<ref>Pubmed, ''[https://www.ncbi.nlm.nih.gov/pubmed/?term=%22malocclusion%22 Malocclusion]''</ref> indicating a lack of uniform terminological consensus on the subject. Among these articles, some may provide conclusions of significant relevance, as strikingly demonstrated by the work of Smaglyuk and colleagues. This particularly significant study explores the interdisciplinary approach in diagnosing malocclusion .............<Div class="colour-button">[[Special:UserLogin&returnto=Introduction+Page|Read the full chapter]]  
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